GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2463822 | 1 | rs2463822 | chr11:62103420 | ASRGL1 | chr11:62104774-62160885:+ | 0.55 | 5.44 | 4.17E-7 | Chronic obstructive pulmonary disease-related biomarkers |
| THYM | cis | rs2463822 | 1 | rs2463825 | chr11:62094493 | ASRGL1 | chr11:62104774-62160885:+ | 0.56 | 5.84 | 7.37E-8 | Chronic obstructive pulmonary disease-related biomarkers |
| THYM | cis | rs2243480 | 1 | rs2465120 | chr7:65620974 | CCT6P1 | chr7:65216092-65228661:+ | 0.65 | 5.41 | 4.64E-7 | Diabetic kidney disease |
| THYM | cis | rs2275426 | 1 | rs2486447 | chr1:46545724 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs9473555 | 1 | rs2501962 | chr6:49453636 | CENPQ | chr6:49431096-49460820:+ | 0.25 | 4.46 | 2.28E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs2501963 | chr6:49454281 | CENPQ | chr6:49431096-49460820:+ | 0.25 | 4.48 | 2.1E-5 | Folate pathway vitamin levels |
| THYM | cis | rs2463822 | 1 | rs2513052 | chr11:62108248 | ASRGL1 | chr11:62104774-62160885:+ | 0.56 | 5.84 | 7.18E-8 | Chronic obstructive pulmonary disease-related biomarkers |
| THYM | cis | rs2463822 | 1 | rs2513071 | chr11:62098387 | ASRGL1 | chr11:62104774-62160885:+ | 0.56 | 5.84 | 7.37E-8 | Chronic obstructive pulmonary disease-related biomarkers |
| THYM | cis | rs2463822 | 1 | rs2513074 | chr11:62100880 | ASRGL1 | chr11:62104774-62160885:+ | 0.56 | 5.84 | 7.37E-8 | Chronic obstructive pulmonary disease-related biomarkers |
| THYM | cis | rs2463822 | 1 | rs2513076 | chr11:62103711 | ASRGL1 | chr11:62104774-62160885:+ | 0.56 | 5.84 | 7.37E-8 | Chronic obstructive pulmonary disease-related biomarkers |
| THYM | cis | rs2463822 | 1 | rs2513744 | chr11:62077785 | ASRGL1 | chr11:62104774-62160885:+ | 0.51 | 5.15 | 1.41E-6 | Chronic obstructive pulmonary disease-related biomarkers |
| THYM | cis | rs2463822 | 1 | rs2513747 | chr11:62098735 | ASRGL1 | chr11:62104774-62160885:+ | 0.56 | 5.84 | 7.37E-8 | Chronic obstructive pulmonary disease-related biomarkers |
| THYM | cis | rs2463822 | 1 | rs2513749 | chr11:62105391 | ASRGL1 | chr11:62104774-62160885:+ | 0.56 | 5.84 | 7.18E-8 | Chronic obstructive pulmonary disease-related biomarkers |
| THYM | cis | rs2524005 | 1 | rs2524005 | chr6:29899677 | ZFP57 | chr6:29640171-29648887:- | 0.83 | 5.37 | 5.52E-7 | Bipolar disorder and schizophrenia |
| THYM | cis | rs252716 | 1 | rs252716 | chr5:110425063 | TSLP | chr5:110405778-110413722:+ | 0.44 | 4.19 | 6.18E-5 | Eosinophilic esophagitis |